Vitronectin Gene Sequence, Family, Fuction and Expression Information

Vitronectin cDNA / Gene Overview

VTN gene / cDNA is a protein-coding gene which located on 17q11.2. The VTN gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog.219 organisms have orthologs with human gene VTN.

Vitronectin cDNA / Gene Function

The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. [provided by RefSeq, Jul 2008]

Vitronectin cDNA / Gene Sequence

LOCUS
LOCUS NM_000638 1678 bp mRNA linear PRI 23-JUN-2018
DEFINITION
Homo sapiens vitronectin (VTN), mRNA.
ACCESSION
NM_000638
VERSION
NM_000638.3

This sequence information is just for reference only.

Vitronectin Family & Reagents

Gene family

Vitronectin Gene family reagents (Endogenous ligands)

Approved Symbol Reagent list
MLN
LGALS1
PROK1
PSAP
CD274
EPO
PPBP
INHBB
CCL11
BMP2
Approved Symbol Reagent list
PTN
ADIPOQ
CALCA
GHRH
CCL3
APP
CCL22
XCL2
CXCL9
BMP5

Vitronectin cDNA / Gene Alias

  • complement S-protein
  • serum spreading factor
  • somatomedin B
  • VN

Vitronectin cDNA / Gene Expression

Restricted expression toward liver (RPKM 1572.2)