TIGIT cDNA Clone: Expression and Clone Vector / Plasmid

TIGIT cDNA / Gene Overview

TIGIT gene / cDNA is a protein-coding gene which located on 3q13.31. The TIGIT gene is conserved in chimpanzee, dog, cow, mouse, and rat.123 organisms have orthologs with human gene TIGIT.

TIGIT cDNA / Gene Function

This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009]

TIGIT cDNA / Gene Sequence

LOCUS
LOCUS NM_173799 2978 bp mRNA linear PRI 08-JUL-2018
DEFINITION
Homo sapiens T cell immunoreceptor with Ig and ITIM domains (TIGIT), mRNA.
ACCESSION
NM_173799
VERSION
NM_173799.3

This sequence information is just for reference only.

TIGIT Family & Reagents

TIGIT Gene family reagents (V-set domain containing)

Approved Symbol Reagent list
CD80
CEACAM3
NCR2
CD83
CD300LB
NECTIN2
PSG1
ESAM
VTCN1
HEPACAM
Approved Symbol Reagent list
MCAM
CD274
CEACAM6
CADM1
BTN3A2
CD7
CD8A
BTN3A1
VSIG8
CEACAM8

TIGIT cDNA / Gene Alias

  • DKFZp667A205
  • FLJ39873

TIGIT cDNA / Gene Expression

Biased expression in lymph node (RPKM 15.1), spleen (RPKM 5.9) and 7 other tissues