SUMO1 Gene Sequence, Family, Fuction and Expression Information

SUMO1 cDNA / Gene Overview

SUMO1 gene / cDNA is a protein-coding gene which located on 2q33.1. The SUMO1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, C.elegans, and frog.236 organisms have orthologs with human gene SUMO1.

SUMO1 cDNA / Gene Function

This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last four amino acids of the carboxy-terminus have been cleaved off. Several pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]

SUMO1 cDNA / Gene Sequence

LOCUS
LOCUS NM_003352 1527 bp mRNA linear PRI 12-AUG-2018
DEFINITION
Homo sapiens small ubiquitin-like modifier 1 (SUMO1), transcript variant 1, mRNA.
ACCESSION
NM_003352
VERSION
NM_003352.4

This sequence information is just for reference only.

SUMO1 cDNA / Gene Alias

  • GMP1
  • OFC10
  • PIC1
  • SMT3C
  • SMT3H3
  • SUMO-1

SUMO1 cDNA / Gene Expression

Ubiquitous expression in thyroid (RPKM 51.9), adrenal (RPKM 51.8) and 25 other tissues