SMYD3 Protein Overview: Sequence, Structure, Function and Protein Interaction

SMYD3 Protein Overview

SMYD3 protein family

Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family.

SMYD3 protein name

Recommended name
Histone-lysine N-methyltransferase SMYD3
Alternative name
SET and MYND domain-containing protein 3 Zinc finger MYND domain-containing protein 1

SMYD3 Gene family protein

SMYD3 Protein Sequence

Species Human SMYD3 protein
Length 428
Mass (Da) 49097
Sequence Human SMYD3 protein sequence
Species Mouse SMYD3 protein
Length 428
Mass (Da) 49126
Sequence Mouse SMYD3 protein sequence
Mass (Da)

SMYD3 Protein Molecular Weight & PI

Histone-lysine N-methyltransferase SMYD3 (EC (SET and MYND domain-containing protein 3) (Zinc finger MYND domain-containing protein 1) Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 1-428 Histone-lysine N-methyltransferase SMYD3.

Molecular weight (Da)


Theoretical pI


SMYD3 Protein Structure

Co-crystal Structure of human SMYD3 with a MEKK2 peptide at 2.13A
2016-01-21   Released:  2016-03-30
Deposition Author(s)
Elkins, P.A., Bonnette, W.G.
Homo sapiens
Expression System
unidentified baculovirus
Experimental Data Snapshot
1.7200 Å
R-Value Free
R-Value Work
5HQ8 From PDB

Human SMYD3 protein Secondary structure

SMYD3 Protein Interaction

Recombinant SMYD3 Protein Feature

SMYD3 Protein, Human, Recombinant (His & FLAG Tag)

High Purity
> 70 % as determined by SDS-PAGE
Low Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method

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