SF3B4 Gene Sequence, Family, Fuction and Expression Information

SF3B4 cDNA / Gene Overview

SF3B4 cDNA / gene is a gene with protein product which located on 1q21.2. The SF3B4 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and zebrafish. 214 organisms have orthologs with human gene SF3B4.

SF3B4 cDNA / Gene Function

This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA. [provided by RefSeq, Jul 2008]

SF3B4 cDNA / Gene Sequence

LOCUS
HUMSAP49A 1275 bp DNA linear PRI 09-JAN-1995
DEFINITION
Human spliceosomal protein (SAP 49) gene, complete cds.
ACCESSION
L35013
VERSION
L35013.1

This sequence information is just for reference only.

SF3B4 Family & Reagents

SF3B4 Gene family reagents (RNA binding motif containing)

Approved Symbol Reagent list
CIRBP
HNRNPR
SSB
Approved Symbol Reagent list
ESRP1
IGF2BP2
   

SF3B4 cDNA / Gene Alias

  • Hsh49
  • SAP49
  • SF3b49

SF3B4 cDNA / Gene Expression

Ubiquitous expression in testis (RPKM 26.0), bone marrow (RPKM 20.1) and 25 other tissues