PI3 Kinase p110 beta/PIK3CB Gene Sequence, Family, Fuction and Expression Information
PI3 Kinase p110 beta/PIK3CB cDNA / Gene Overview
PIK3CB gene / cDNA is a protein-coding gene which located on 3q22.3. The PIK3CB gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog.235 organisms have orthologs with human gene PIK3CB.
This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
PI3 Kinase p110 beta/PIK3CB cDNA / Gene Sequence
LOCUS NM_001256045 4797 bp mRNA linear PRI 05-AUG-2018