PI3 Kinase p110 beta/PIK3CB Gene Sequence, Family, Fuction and Expression Information

PI3 Kinase p110 beta/PIK3CB cDNA / Gene Overview

PIK3CB gene / cDNA is a protein-coding gene which located on 3q22.3. The PIK3CB gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog.235 organisms have orthologs with human gene PIK3CB.

PI3 Kinase p110 beta/PIK3CB cDNA / Gene Function

This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]

PI3 Kinase p110 beta/PIK3CB cDNA / Gene Sequence

LOCUS NM_001256045 4797 bp mRNA linear PRI 05-AUG-2018
Homo sapiens phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta (PIK3CB), transcript variant 2, mRNA.

This sequence information is just for reference only.

PI3 Kinase p110 beta/PIK3CB cDNA / Gene Expression

Ubiquitous expression in thyroid (RPKM 19.2), kidney (RPKM 9.0) and 25 other tissues