PIK3CA Gene Sequence, Family, Fuction and Expression Information

PIK3CA cDNA / Gene Overview

PIK3CA gene / cDNA is a protein-coding gene which located on 3q26.32. The PIK3CA gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, C.elegans, and frog.223 organisms have orthologs with human gene PIK3CA.

PIK3CA cDNA / Gene Function

Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22. [provided by RefSeq, Apr 2016]

PIK3CA cDNA / Gene Sequence

LOCUS
LOCUS NM_006218 9104 bp mRNA linear PRI 12-AUG-2018
DEFINITION
Homo sapiens phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA), mRNA.
ACCESSION
NM_006218
VERSION
NM_006218.3

This sequence information is just for reference only.

PIK3CA cDNA / Gene Alias

  • PI3K

PIK3CA cDNA / Gene Expression

Ubiquitous expression in fat (RPKM 10.3), gall bladder (RPKM 7.8) and 25 other tissues