MCP-1/CCL2 Information: MCP-1/CCL2 Protein, MCP-1/CCL2 Antibody and MCP-1/CCL2 Gene

MCP-1/CCL2 Gene family

MCP-1/CCL2 Protein

MCP-1/CCL2 protein function

Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.

MCP-1/CCL2 protein expression

Tissue specificity

Expressed in the seminal plasma, endometrial fluid and follicular fluid (at protein level).

Induction

Up-regulated upon hypertonic conditions (PubMed:23233732). In pancreatic islets, secretion is stimulated by IL1B (PubMed:23955712).

MCP-1/CCL2 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    99.00
  • Mass (Da)
    11.00

MCP-1/CCL2 Antibody

There are 14 MCP-1/CCL2 antibodies which are validated in multiple tissues with various applications, including ELISA, ELISA(Cap), ELISA(Det), IHC-P, ICC/IF. There are 11 MCP-1/CCL2 antibody for ELISA, 2 MCP-1/CCL2 antibody for ELISA(Cap), 2 MCP-1/CCL2 antibody for ELISA(Det), 3 MCP-1/CCL2 antibody for IHC-P, 1 MCP-1/CCL2 antibody for ICC/IF. Among all these MCP-1/CCL2 antibodies, there are 2 anti-MCP-1/CCL2 mouse monoclonal antibodies , 6 anti-MCP-1/CCL2 rabbit monoclonal antibodies , 6 anti-MCP-1/CCL2 rabbit polyclonal antibodies . All the MCP-1/CCL2 anbodies are produced in house and all are in stock. MCP-1/CCL2 antibody customerized service is available.

MCP-1/CCL2 Gene

CCL2 gene / cDNA is a protein-coding gene which located on 17q12. The CCL2 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat.26 organisms have orthologs with human gene CCL2.