MASP2 Protein Overview: Sequence, Structure, Function and Protein Interaction

MASP2 Protein Overview

MASP2 protein family

Belongs to the peptidase S1 family.

MASP2 protein name

Recommended name
Mannan-binding lectin serine protease 2
Short name
MASP-2
Alternative name
MBL-associated serine protease 2 Mannose-binding protein-associated serine protease 2 Mannan-binding lectin serine protease 2 A chain Mannan-binding lectin serine protease 2 B chain

MASP2 Protein Sequence

Species Human MASP2 protein
Length 686
Mass (Da) 75702
Sequence Human MASP2 protein sequence
Species Mouse MASP2 protein
Length 685
Mass (Da) 75517
Sequence Mouse MASP2 protein sequence
Species Rat MASP2 protein
Length 685
Mass (Da) 75667
Sequence Rat MASP2 protein sequence

MASP2 Protein Molecular Weight & PI

Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (MBL-associated serine protease 2) (Mannose-binding protein-associated serine protease 2) (MASP-2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain] Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 16-686 Mannan-binding lectin serine protease 2.

Molecular weight (Da)

74160.39

Theoretical pI

5.34

MASP2 Protein Structure

Crystal structure of the catalytic region of human MASP-2
Deposited
2003-08-01   Released:  2004-08-03
Deposition Author(s)
Harmat, V., Gal, P., Kardos, J., Szilagyi, K., Ambrus, G., Naray-Szabo, G., Zavodszky, P.
Organism(s)
Homo sapiens
Expression System
Escherichia coli BL21(DE3)
Experimental Data Snapshot
Method
X-RAY DIFFRACTION
Resolution
2.2300 Å
R-Value Free
0.224
R-Value Work
0.174
1Q3X From PDB

Human MASP2 protein Secondary structure

MASP2 Protein Interaction

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