IP-10/CXCL10 Gene Sequence, Family, Fuction and Expression Information

IP-10/CXCL10 cDNA / Gene Overview

CXCL10 gene / cDNA is a protein-coding gene which located on 4q21.1. The CXCL10 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat.112 organisms have orthologs with human gene CXCL10.

IP-10/CXCL10 cDNA / Gene Function

This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. [provided by RefSeq, Sep 2014]

IP-10/CXCL10 cDNA / Gene Sequence

LOCUS
LOCUS NM_001565 1227 bp mRNA linear PRI 22-JUL-2018
DEFINITION
Homo sapiens C-X-C motif chemokine ligand 10 (CXCL10), mRNA.
ACCESSION
NM_001565
VERSION
NM_001565.3

This sequence information is just for reference only.

IP-10/CXCL10 Family & Reagents

IP-10/CXCL10 Gene family reagents (Chemokine ligands)

Approved Symbol Reagent list
CCL1
CCL14
XCL1
CCL18
CCL5
CCL27
CCL28
CXCL9
CCL4
CCL21
Approved Symbol Reagent list
CXCL11
CXCL8
CXCL14
CXCL5
CXCL12
CXCL16
CCL16
CCL11
CXCL3
CXCL1

IP-10/CXCL10 Gene family reagents (Endogenous ligands)

Approved Symbol Reagent list
ADIPOQ
FN1
RAC1
CCL20
AGT
GIP
CCL7
CCL23
BID
CXCL1
Approved Symbol Reagent list
Fgf8
CSF3
CX3CL1
FGF6
CXCL9
CCL4
ICAM1
CD274
RSPO3
THPO

IP-10/CXCL10 cDNA / Gene Alias

  • C7
  • crg-2
  • gIP-10
  • IFI10
  • IP-10
  • mob-1

IP-10/CXCL10 cDNA / Gene Expression

Broad expression in appendix (RPKM 54.9), lymph node (RPKM 28.7) and 14 other tissues