IL21 Information: IL21 Protein, IL21 Antibody and IL21 Gene

IL21 Gene family

IL21 Protein

IL21 protein function

Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. {ECO:0000250, ECO:0000269|PubMed:11081504, ECO:0000269|PubMed:15178704}.

IL21 protein expression

Tissue specificity

Expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes.

IL21 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    155.00
  • Mass (Da)
    17.00

IL21 Antibody

There are 12 IL21 antibodies which are validated in multiple tissues with various applications, including ELISA, WB. There are 11 IL21 antibody for ELISA, 2 IL21 antibody for WB. Among all these IL21 antibodies, there are 1 anti-IL21 mouse monoclonal antibodies , 3 anti-IL21 rabbit monoclonal antibodies , 8 anti-IL21 rabbit polyclonal antibodies . All the IL21 anbodies are produced in house and all are in stock. IL21 antibody customerized service is available.

IL21 Gene

IL21 gene / cDNA is a protein-coding gene which located on 4q27. The IL21 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat.157 organisms have orthologs with human gene IL21.