IFNGR1 Gene Sequence, Family, Fuction and Expression Information
IFNGR1 cDNA / Gene Overview
IFNGR1 gene / cDNA is a protein-coding gene which located on 6q23.3. The IFNGR1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and frog.208 organisms have orthologs with human gene IFNGR1.
This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008]
IFNGR1 cDNA / Gene Sequence
LOCUS NM_000416 2138 bp mRNA linear PRI 22-JUL-2018