IFNGR1 Gene Sequence, Family, Fuction and Expression Information

IFNGR1 cDNA / Gene Overview

IFNGR1 gene / cDNA is a protein-coding gene which located on 6q23.3. The IFNGR1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and frog.208 organisms have orthologs with human gene IFNGR1.

IFNGR1 cDNA / Gene Function

This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008]

IFNGR1 cDNA / Gene Sequence

LOCUS
LOCUS NM_000416 2138 bp mRNA linear PRI 22-JUL-2018
DEFINITION
Homo sapiens interferon gamma receptor 1 (IFNGR1), transcript variant 1, mRNA.
ACCESSION
NM_000416
VERSION
NM_000416.2

This sequence information is just for reference only.

IFNGR1 Family & Reagents

IFNGR1 Gene family reagents (CD molecules)

Approved Symbol Reagent list
LY9
IL5RA
LAMP3
TLR3
CD53
CD68
TNFRSF21
CSF2RB
IL13Ra2
CD70
Approved Symbol Reagent list
CTLA4
ENPP3
CD96
B3gat1
FAS
NCR3
TNFRSF14
LAIR2
TNFRSF10C
CD180

IFNGR1 Gene family reagents (Interferon receptors)

Approved Symbol Reagent list
IFNAR1
IFNGR2
Approved Symbol Reagent list
IFNAR2
   

IFNGR1 cDNA / Gene Alias

  • CD119

IFNGR1 cDNA / Gene Expression

Ubiquitous expression in spleen (RPKM 51.4), fat (RPKM 48.1) and 25 other tissues

Recombinant IFNGR1 protein citations

Title
Adipose tissue-derived mesenchymal stem cells have a heterogenic cytokine secretion profile
Year
2017
Author
Wu, Y;Hoogduijn, MJ;Baan, CC;Korevaar, SS;de Kuiper, R;Yan, L;Wang, L;van Besouw, NM;
Journal
Hindawi Stem Cells International