GSK3B Gene Sequence, Family, Fuction and Expression Information
GSK3B cDNA / Gene Overview
GSK3B gene / cDNA is a protein-coding gene which located on 3q13.33. The GSK3B gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, C.elegans, A.thaliana, rice, and frog.222 organisms have orthologs with human gene GSK3B.
The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease. [provided by RefSeq, Aug 2017]
GSK3B cDNA / Gene Sequence
LOCUS NM_001146156 7095 bp mRNA linear PRI 05-AUG-2018