Fibronectin Gene Sequence, Family, Fuction and Expression Information
Fibronectin cDNA / Gene Overview
FN1 gene / cDNA is a protein-coding gene which located on 2q35. The FN1 gene is conserved in chimpanzee, Rhesus monkey, dog, mouse, rat, chicken, zebrafish, and frog.207 organisms have orthologs with human gene FN1.
This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined. [provided by RefSeq, Jan 2016]
Fibronectin cDNA / Gene Sequence
LOCUS NM_212476 8290 bp mRNA linear PRI 03-JUN-2018
Homo sapiens fibronectin 1 (FN1), transcript variant 5, mRNA.
This sequence information is just for reference only.