EphA3 Gene Sequence, Family, Fuction and Expression Information
EphA3 cDNA / Gene Overview
EphA3 gene / cDNA is a protein-coding gene which located on 3p11.1. The EPHA3 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and frog.201 organisms have orthologs with human gene EPHA3.
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]
EphA3 cDNA / Gene Sequence
LOCUS NM_005233 5837 bp mRNA linear PRI 08-JUL-2018
Homo sapiens EPH receptor A3 (EPHA3), transcript variant 1, mRNA.
This sequence information is just for reference only.