EphA3 Gene Sequence, Family, Fuction and Expression Information

EphA3 cDNA / Gene Overview

EphA3 gene / cDNA is a protein-coding gene which located on 3p11.1. The EPHA3 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and frog.201 organisms have orthologs with human gene EPHA3.

EphA3 cDNA / Gene Function

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]

EphA3 cDNA / Gene Sequence

LOCUS
LOCUS NM_005233 5837 bp mRNA linear PRI 08-JUL-2018
DEFINITION
Homo sapiens EPH receptor A3 (EPHA3), transcript variant 1, mRNA.
ACCESSION
NM_005233
VERSION
NM_005233.5

This sequence information is just for reference only.

EphA3 Family & Reagents

EphA3 Gene family reagents (Fibronectin type III domain containing)

Approved Symbol Reagent list
FLRT1
FN1
CNTN6
EphA2
EphB6
CSF2RB
NCAM1
NCAM2
MPL
FNDC4
Approved Symbol Reagent list
PTPRJ
EphA4
Tie1
EPHA8
IL20RB
L1CAM
CNTN4
OSMR
GHR
CHL1

EphA3 Gene family reagents (Sterile alpha motif domain containing)

Approved Symbol Reagent list
CNKSR3
EphA2
EphA6
EPHA8
EphB2
EphB4
STIM1
Approved Symbol Reagent list
EPHA1
EphA4
EphA7
EphB1
EphB3
EphB6
   

EphA3 Gene family reagents (EPH receptors)

Approved Symbol Reagent list
EPHA1
EphA4
EphA7
EphB1
EphB3
EphB6
Approved Symbol Reagent list
EphA2
EphA6
EPHA8
EphB2
EphB4
   

EphA3 cDNA / Gene Alias

  • HEK
  • HEK4

EphA3 cDNA / Gene Expression

Broad expression in prostate (RPKM 12.7), gall bladder (RPKM 11.9) and 18 other tissues