ECE2 Protein Overview: Sequence, Structure, Function and Protein Interaction

ECE2 Protein Overview

Endothelin-converting enzymes, such as ECE2 (EC 3.4.24.71), are type II metalloproteases that generate functionally pleiotropic members of the endothelin vasoactive peptide family (Lorenzo et al., 2001).

ECE2 protein family

Belongs to the peptidase M13 family.

ECE2 protein name

Recommended name
Endothelin-converting enzyme 2
Short name
ECE-2
Aliases
KIAA0604, MGC2408

ECE2 Gene family protein

M13 metallopeptidases
Approved symbol Common name
ECE1 ECE1 protein, recombinant
MME CD10 protein, recombinant

ECE2 Protein Sequence

Species Human ECE2 protein
Length 811
Mass (Da) 91211
Sequence Human ECE2 protein sequence
Species Mouse ECE2 protein
Length 763
Mass (Da) 86231
Sequence Mouse ECE2 protein sequence
Species
Length
Mass (Da)
Sequence

ECE2 Protein Molecular Weight & PI

Endothelin-converting enzyme 2 (EC 3.4.24.71) (ECE-2) Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 1-811 Endothelin-converting enzyme 2.

Molecular weight (Da)

91211.04

Theoretical pI

5.19

ECE2 Protein Interaction

Recombinant ECE2 Protein Feature

ECE2 Protein, Human, Recombinant (His Tag)

High Purity
> 93 % as determined by SDS-PAGE
Low Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method

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