E-Cadherin Information: E-Cadherin Protein, E-Cadherin Antibody and E-Cadherin Gene

E-Cadherin Gene family

E-Cadherin Protein

E-Cadherin protein function

Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed:11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. {ECO:0000269|PubMed:11976333, ECO:0000269|PubMed:16417575}.; E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production. {ECO:0000269|PubMed:16417575}.

E-Cadherin protein expression

Tissue specificity

Non-neural epithelial tissues.

Induction

Expression is repressed by MACROD1.

E-Cadherin protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    882.00
  • Mass (Da)
    97.00

E-Cadherin Antibody

There are 21 E-Cadherin antibodies which are validated in multiple tissues with various applications, including ELISA(Cap), ICC/IF, ELISA, FCM, IHC-P, WB, IP. There are 1 E-Cadherin antibody for ELISA(Cap), 7 E-Cadherin antibody for ICC/IF, 13 E-Cadherin antibody for ELISA, 4 E-Cadherin antibody for FCM, 5 E-Cadherin antibody for IHC-P, 6 E-Cadherin antibody for WB, 4 E-Cadherin antibody for IP. Among all these E-Cadherin antibodies, there are 8 anti-E-Cadherin mouse monoclonal antibodies , 5 anti-E-Cadherin rabbit monoclonal antibodies , 8 anti-E-Cadherin rabbit polyclonal antibodies . All the E-Cadherin anbodies are produced in house and all are in stock. E-Cadherin antibody customerized service is available.

E-Cadherin Gene

CDH1 gene / cDNA is a protein-coding gene which located on 16q22.1. The CDH1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog.136 organisms have orthologs with human gene CDH1.