DcR3 Gene Sequence, Family, Fuction and Expression Information

DcR3 cDNA / Gene Overview

TNFRSF6B gene / cDNA is a protein-coding gene which located on 20q13.33. The TNFRSF6B gene is conserved in Rhesus monkey, dog, cow, and chicken.165 organisms have orthologs with human gene TNFRSF6B.

DcR3 cDNA / Gene Function

This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript. [provided by RefSeq, Feb 2011]

DcR3 cDNA / Gene Sequence

LOCUS
LOCUS NM_003823 1155 bp mRNA linear PRI 25-JUN-2018
DEFINITION
Homo sapiens TNF receptor superfamily member 6b (TNFRSF6B), mRNA.
ACCESSION
NM_003823
VERSION
NM_003823.3

This sequence information is just for reference only.

DcR3 Family & Reagents

DcR3 Gene family reagents (Tumor necrosis factor receptor superfamily)

Approved Symbol Reagent list
FAS
TNFRSF4
CD40
TNFRSF13C
TNFRSF13B
LTBR
TNFRSF1B
TNFRSF14
TNFRSF9
TNFRSF11B
Approved Symbol Reagent list
NGFR
TNFRSF10B
TNFRSF17
TNFRSF10C
CD27
TNFRSF1A
TNFRSF11A
TNFRSF12A
EDA2R
TNFRSF10A

DcR3 cDNA / Gene Alias

  • DcR3
  • DCR3
  • M68
  • TR6

DcR3 cDNA / Gene Expression

Broad expression in appendix (RPKM 7.2), spleen (RPKM 3.2) and 20 other tissues