CEACAM5 Information: CEACAM5 Protein, CEACAM5 Antibody and CEACAM5 Gene

CEACAM5 Gene family

CEACAM5 Protein

CEACAM5 protein function

Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:2803308, PubMed:10910050, PubMed:10864933). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:2803308). Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells (PubMed:10910050). {ECO:0000269|PubMed:10864933, ECO:0000269|PubMed:10910050, ECO:0000269|PubMed:2803308}.; (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. {ECO:0000269|PubMed:18086185}.

CEACAM5 protein expression

Tissue specificity

Expressed in columnar epithelial and goblet cells of the colon (at protein level) (PubMed:10436421). Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.

CEACAM5 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    702.00
  • Mass (KDa)
    76.00

CEACAM5 Antibody

There are 19 CEACAM5 antibodies which are validated in multiple tissues with various applications, including ELISA(Cap), FCM, ELISA(Det), ELISA, IHC-P. There are 1 CEACAM5 antibody for ELISA(Cap), 5 CEACAM5 antibody for FCM, 1 CEACAM5 antibody for ELISA(Det), 11 CEACAM5 antibody for ELISA, 2 CEACAM5 antibody for IHC-P. Among all these CEACAM5 antibodies, there are 9 anti-CEACAM5 mouse monoclonal antibodies , 8 anti-CEACAM5 rabbit monoclonal antibodies , 2 anti-CEACAM5 rabbit polyclonal antibodies . All the CEACAM5 anbodies are produced in house and all are in stock. CEACAM5 antibody customerized service is available.

CEACAM5 Gene

CEACAM5 gene / cDNA is a protein-coding gene which located on 19q13.2. The CEACAM5 gene is conserved in chimpanzee, Rhesus monkey, and zebrafish.15 organisms have orthologs with human gene CEACAM5.