The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]
CD70 cDNA / Gene Sequence
LOCUS NM_001252 913 bp mRNA linear PRI 29-JUL-2018
Homo sapiens CD70 molecule (CD70), transcript variant 1, mRNA.
This sequence information is just for reference only.