CD55/DAF Information: CD55/DAF Protein, CD55/DAF Antibody and CD55/DAF Gene

CD55/DAF Gene family

CD55/DAF Protein

CD55/DAF protein function

This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade (PubMed:7525274). Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage (PubMed:28657829). {ECO:0000269|PubMed:7525274, ECO:0000305|PubMed:28657829}.; (Microbial infection) Acts as a receptor for Coxsackievirus A21, coxsackieviruses B1, B3 and B5. {ECO:0000269|PubMed:9151867}.; (Microbial infection) Acts as a receptor for Human enterovirus 70 and D68 (Probable). {ECO:0000269|PubMed:8764022}.; (Microbial infection) Acts as a receptor for Human echoviruses 6, 7, 11, 12, 20 and 21. {ECO:0000269|PubMed:7525274, ECO:0000305|PubMed:12409401}.

CD55/DAF protein expression

Tissue specificity

Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix.

CD55/DAF protein sequence

This sequence information is just for reference only.From Uniport

  • Length
  • Mass (Da)

CD55/DAF Antibody

There are 21 CD55/DAF antibodies which are validated in multiple tissues with various applications, including ELISA, ELISA(Det), FCM, ELISA(Cap), ICC/IF, WB, IHC-P, IP. There are 7 CD55/DAF antibody for ELISA, 1 CD55/DAF antibody for ELISA(Det), 15 CD55/DAF antibody for FCM, 2 CD55/DAF antibody for ELISA(Cap), 2 CD55/DAF antibody for ICC/IF, 1 CD55/DAF antibody for WB, 1 CD55/DAF antibody for IHC-P, 1 CD55/DAF antibody for IP. Among all these CD55/DAF antibodies, there are 6 anti-CD55/DAF mouse monoclonal antibodies , 11 anti-CD55/DAF rabbit monoclonal antibodies , 4 anti-CD55/DAF rabbit polyclonal antibodies . All the CD55/DAF anbodies are produced in house and all are in stock. CD55/DAF antibody customerized service is available.

CD55/DAF Gene

CD55 gene / cDNA is a protein-coding gene which located on 1q32.2. The CD55 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat.145 organisms have orthologs with human gene CD55.