CD47 Gene Sequence, Family, Fuction and Expression Information
CD47 cDNA / Gene Overview
CD47 gene / cDNA is a protein-coding gene which located on 3q13.12. The CD47 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and chicken.189 organisms have orthologs with human gene CD47.
This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]
CD47 cDNA / Gene Sequence
LOCUS NM_001777 5346 bp mRNA linear PRI 11-AUG-2018
Homo sapiens CD47 molecule (CD47), transcript variant 1, mRNA.
This sequence information is just for reference only.