CD47 Gene Sequence, Family, Fuction and Expression Information

CD47 cDNA / Gene Overview

CD47 gene / cDNA is a protein-coding gene which located on 3q13.12. The CD47 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and chicken.189 organisms have orthologs with human gene CD47.

CD47 cDNA / Gene Function

This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]

CD47 cDNA / Gene Sequence

LOCUS
LOCUS NM_001777 5346 bp mRNA linear PRI 11-AUG-2018
DEFINITION
Homo sapiens CD47 molecule (CD47), transcript variant 1, mRNA.
ACCESSION
NM_001777
VERSION
NM_001777.3

This sequence information is just for reference only.

CD47 Family & Reagents

CD47 Gene family reagents (CD molecules)

Approved Symbol Reagent list
IL10RA
PTPRC
NECTIN1
CD83
SLAMF6
TLR4
CEACAM3
PDCD1
TNFSF10
CD99
Approved Symbol Reagent list
CD247
TNFRSF13C
BMPR1A
FGFR1
TNFRSF10C
BMPR1B
BST2
HAVCR1
ADAM8
LEPR

CD47 Gene family reagents (Immunoglobulin like domain containing)

Approved Symbol Reagent list
CSF1R
KIRREL1
NCR1
AGER
CNTN4
KIT
CHL1
MERTK
LEPR
NECTIN1
Approved Symbol Reagent list
CADM3
CADM4
CD200
LY9
THY1
BCAM
CD86
FCGR3B
MDGA2
TMIGD2

CD47 Gene family reagents (Ig-like cell adhesion molecule family)

Approved Symbol Reagent list
L1CAM
CD84
BCAM
CADM4
CNTN5
HEPACAM
CD2
ICAM5
ALCAM
FGFRL1
Approved Symbol Reagent list
CD58
CNTN1
JAM3
ICAM2
NFASC
CNTN4
CADM3
NECTIN1
UNC5A
ROBO2

CD47 cDNA / Gene Alias

  • antigen identified by monoclonal antibody 1D8
  • antigenic surface determinant protein OA3
  • CD47 glycoprotein
  • IAP
  • integrin associated protein
  • leukocyte surface antigen CD47
  • OA3
  • Rh-related antigen

CD47 cDNA / Gene Expression

Ubiquitous expression in lung (RPKM 24.2), brain (RPKM 20.9) and 24 other tissues