CD3G Gene Sequence, Family, Fuction and Expression Information

CD3G cDNA / Gene Overview

CD3G gene / cDNA is a protein-coding gene which located on 11q23.3. The CD3G gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat.127 organisms have orthologs with human gene CD3G.

CD3G cDNA / Gene Function

The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. [provided by RefSeq, Jul 2008]

CD3G cDNA / Gene Sequence

LOCUS
LOCUS NM_000073 1311 bp mRNA linear PRI 23-JUN-2018
DEFINITION
Homo sapiens CD3g molecule (CD3G), mRNA.
ACCESSION
NM_000073
VERSION
NM_000073.2

This sequence information is just for reference only.

CD3G Family & Reagents

Gene family

CD3G Gene family reagents (CD molecules)

Approved Symbol Reagent list
CD300A
TNFRSF13C
IL6ST
CD68
CD59
NECTIN3
MSR1
LILRA3
SIRPG
LY75
Approved Symbol Reagent list
PTPRJ
ENTPD1
TNFRSF11A
CD8B
CD300E
TREM1
IGSF8
SLAMF6
ENG
TNFSF11

CD3G cDNA / Gene Expression

Biased expression in lymph node (RPKM 14.5), appendix (RPKM 7.1) and 9 other tissues