CD200 Gene Sequence, Family, Fuction and Expression Information

CD200 cDNA / Gene Overview

CD200 gene / cDNA is a protein-coding gene which located on 3q13.2. The CD200 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and chicken.123 organisms have orthologs with human gene CD200.

CD200 cDNA / Gene Function

This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

CD200 cDNA / Gene Sequence

LOCUS
LOCUS NM_001004196 2423 bp mRNA linear PRI 11-AUG-2018
DEFINITION
Homo sapiens CD200 molecule (CD200), transcript variant 2, mRNA.
ACCESSION
NM_001004196
VERSION
NM_001004196.3

This sequence information is just for reference only.

CD200 Family & Reagents

CD200 Gene family reagents (CD molecules)

Approved Symbol Reagent list
IL2RA
CLEC10A
IL18RAP
FGFR3
BST2
SELE
IL3Ra
CD300C
BTN3A1
TNFRSF13C
Approved Symbol Reagent list
CD180
TEK
TFRC
CD24
F3
PDCD1
LILRA3
CD7
GP1BA
PDGFRA

CD200 Gene family reagents (Immunoglobulin like domain containing)

Approved Symbol Reagent list
CEACAM1
CNTN3
FCER1A
CD48
CSF1R
VSTM1
CEACAM8
VTCN1
AXL
NECTIN3
Approved Symbol Reagent list
NPTN
CD244
IL1RAP
CNTN5
Tie1
F11R
ESAM
PTK7
HEPACAM
CADM4

CD200 cDNA / Gene Alias

  • MRC
  • OX-2

CD200 cDNA / Gene Expression

Broad expression in brain (RPKM 5.4), placenta (RPKM 3.5) and 22 other tissues

Recombinant CD200 protein citations

Title
Evaluation of soluble CD200 levels in type 2 diabetic foot and nephropathic patients: association with disease activity
Year
2014
Author
Arik, HO;Yalcin, AD;Celik, B;Seyman, D;Tetik, G;Gursoy, B;Kose, S;Gumuslu, S;
Journal
Med. Sci. Monit.
Title
Evaluation of soluble CD200 levels in type 2 diabetic foot and nephropathic patients: association with disease activity
Year
2014
Author
Arik, HO;Yalcin, AD;Celik, B;Seyman, D;Tetik, G;Gursoy, B;Kose, S;Gumuslu, S;
Journal
Med. Sci. Monit.