CD19 Gene Sequence, Family, Fuction and Expression Information

CD19 cDNA / Gene Overview

CD19 gene / cDNA is a protein-coding gene which located on 16p11.2. The CD19 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat.118 organisms have orthologs with human gene CD19.

CD19 cDNA / Gene Function

Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. [provided by RefSeq, Jul 2008]

CD19 cDNA / Gene Sequence

LOCUS
LOCUS NM_001178098 1968 bp mRNA linear PRI 24-JUN-2018
DEFINITION
Homo sapiens CD19 molecule (CD19), transcript variant 1, mRNA.
ACCESSION
NM_001178098
VERSION
NM_001178098.1

This sequence information is just for reference only.

CD19 Family & Reagents

CD19 Gene family reagents (CD molecules)

Approved Symbol Reagent list
FCGR1A
PROCR
MS4A1
CTLA4
IL2RG
ADGRE5
NECTIN1
FAS
TNFRSF8
CD8B
Approved Symbol Reagent list
TNFRSF11A
ITGB1
CD22
CLEC12A
ALCAM
PDCD1
FCRL1
CD52
DPP4
TLR4

CD19 Gene family reagents (Immunoglobulin like domain containing)

Approved Symbol Reagent list
CNTN1
NTRK1
ALCAM
Tie1
BTLA
IL18RAP
CDON
FLT3
FCRL2
CD200
Approved Symbol Reagent list
TEK
AMIGO2
ICAM5
LAG3
KIRREL3
A1BG
CNTN5
LAIR2
CD48
VCAM1

CD19 Gene family reagents (Minor histocompatibility antigens)

Approved Symbol Reagent list
BCL2A1
ERBB2
SSR1
Approved Symbol Reagent list
CTSH
LY75
TRIP10

CD19 cDNA / Gene Expression

Biased expression in lymph node (RPKM 43.1), spleen (RPKM 28.3) and 3 other tissues