Argonaute-2 Gene Sequence, Family, Fuction and Expression Information

Argonaute-2 cDNA / Gene Overview

AGO2 gene / cDNA is a protein-coding gene which located on 8q24.3. The AGO2 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, A.thaliana, and frog.192 organisms have orthologs with human gene AGO2.

Argonaute-2 cDNA / Gene Function

This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Argonaute-2 cDNA / Gene Sequence

LOCUS
LOCUS NM_012154 14513 bp mRNA linear PRI 11-JUN-2018
DEFINITION
Homo sapiens argonaute 2, RISC catalytic component (AGO2), transcript variant 1, mRNA.
ACCESSION
NM_012154
VERSION
NM_012154.4

This sequence information is just for reference only.

Argonaute-2 Family & Reagents

Gene family

Argonaute-2 Gene family reagents (Argonaute/PIWI family)

Approved Symbol Reagent list
AGO1
Approved Symbol Reagent list
AGO3

Argonaute-2 cDNA / Gene Alias

  • argonaute 2
  • hAGO2
  • LINC00980
  • Q10

Argonaute-2 cDNA / Gene Expression

Ubiquitous expression in skin (RPKM 3.3), ovary (RPKM 3.3) and 25 other tissues