Argonaute-2 Gene Sequence, Family, Fuction and Expression Information
Argonaute-2 cDNA / Gene Overview
AGO2 gene / cDNA is a protein-coding gene which located on 8q24.3. The AGO2 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, A.thaliana, and frog.192 organisms have orthologs with human gene AGO2.
This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Argonaute-2 cDNA / Gene Sequence
LOCUS NM_012154 14513 bp mRNA linear PRI 11-JUN-2018