Granulocytes are a type of white blood cell that has small granules, which contain proteins. The specific types of granulocytes are neutrophils, eosinophils, and basophils. Basophils express several adhesion molecules which play a critical role in homing, including LFA-1 (CD11a/CD18), Mac-1 (CD11b/CD18), and CD44. Eosinophils respond to chemokine attractants secreted by lymphocytes and neutrophils, such as CCL11/eotaxin-1, CCL24/eotaxin-2, and CCL5/RANTES. Granulocytes, specifically neutrophils, help the body fight bacterial infections. The number of granulocytes in the body usually increases when there is a serious infection. People with a lower number of granulocytes are more likely to develop bad infections more often. Their role is to attack foreign substances that cause inflammation or infection.