| CD352 Gene ID | 114836 |
| CD352 Official Full Name | SLAM family member 6 |
| CD352 Alias | NTB-A, SLAMF6, LY108 |
| CD352 Cellular Expression | T; B; NK; Dendritic; Granulocyte; Macrophage |
| CD352 Ligand/Receptor/Association | CD352 |
| CD352 Function | Triggers cytolytic activity only in NK cells expressing high surface densities of natural cytotoxicity receptors |
| CD352 Summary | The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010] |
Information from NCBI or Wiki
