CD312 antigens

CD312 antigens general information

CD312 Gene ID 30817
CD312 Official Full Name adhesion G protein-coupled receptor E2
CD312 Alias ADGRE2, VBU, EMR2
CD312 Cellular Expression Dendritic; Macrophage; monocytes
CD312 Ligand/Receptor/Association chondroitin sulfates, glycosaminoglycan, CD55
CD312 Function involved in immune and inflammatory response
CD312 Summary This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]

Information from NCBI or Wiki

Tips: We list all the CD antigens according to the specific name of CD molecules.