| CD312 Gene ID | 30817 |
| CD312 Official Full Name | adhesion G protein-coupled receptor E2 |
| CD312 Alias | ADGRE2, VBU, EMR2 |
| CD312 Cellular Expression | Dendritic; Macrophage; monocytes |
| CD312 Ligand/Receptor/Association | chondroitin sulfates, glycosaminoglycan, CD55 |
| CD312 Function | involved in immune and inflammatory response |
| CD312 Summary | This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012] |
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