CD27 antigens

CD27 antigens general information

CD27 Gene ID 939
CD27 Official Full Name CD27 molecule
CD27 Alias T14, TNFRSF 7, CD27L receptor
CD27 Cellular Expression T; B; NK
CD27 Ligand/Receptor/Association CD70
CD27 Function Costimulation of B- and T-cell activation
CD27 Summary The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]

Information from NCBI or Wiki

Tips: We list all the CD antigens according to the specific name of CD molecules.