CD256 antigens

CD256 antigens general information

CD256 Gene ID 8741
CD256 Official Full Name tumor necrosis factor superfamily member 13
CD256 Alias APRIL, TALL-2, TRDL-1, TNFSF13
CD256 Cellular Expression T; Dendritic; Granulocyte; Macrophage
CD256 Ligand/Receptor/Association TACI, BCMA
CD256 Function Important for B cell development
CD256 Summary The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]

Information from NCBI or Wiki

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