CD236 antigens

CD236 antigens general information

CD236 Gene ID 2995
CD236 Official Full Name glycophorin C (Gerbich blood group)
CD236 Alias Glycophorin C/D, GYPC
CD236 Cellular Expression Erythrocyte; Stem cell
CD236 Ligand/Receptor/Association  
CD236 Function Glycophorin-C regulates the stability of red cells
CD236 Summary Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]

Information from NCBI or Wiki

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