CD226 antigens

CD226 antigens general information

CD226 Gene ID 10666
CD226 Official Full Name CD226 molecule
CD226 Alias DNAM-1, PTA-1, TLiSA1
CD226 Cellular Expression T; B; NK; Macrophage; monocytes; Platelet; Stem cell
CD226 Ligand/Receptor/Association CD155, CD112
CD226 Function Intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-cells and NK cells
CD226 Summary This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

Information from NCBI or Wiki

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