CD213a1 antigens

CD213a1 antigens general information

CD213a1 Gene ID 3597
CD213a1 Official Full Name interleukin 13 receptor subunit alpha 1
CD213a1 Alias IL-13-R α1, IL13RA1
CD213a1 Cellular Expression B; Dendritic; Endothelial; Macrophage; monocytes
CD213a1 Ligand/Receptor/Association IL-13
CD213a1 Function Forms part of the receptor complexes for IL13 and IL4
CD213a1 Summary The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. [provided by RefSeq, Jul 2008]

Information from NCBI or Wiki

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