CD210 antigens

CD210 antigens general information

CD210 Gene ID 3587
CD210 Official Full Name interleukin 10 receptor subunit alpha
CD210 Alias IL10RA; IL10R; CD210a; CDW210A; HIL-10R; IL-10R1
CD210 Cellular Expression T; B; NK; Dendritic; Macrophage
CD210 Ligand/Receptor/Association IL-10
CD210 Function CD210 is tha receptor of il-10.
CD210 Summary The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009]

Information from NCBI or Wiki

Tips: We list all the CD antigens according to the specific name of CD molecules.