CD1d antigens

CD1d antigens general information

CD1d Gene ID 912
CD1d Official Full Name CD1d molecule
CD1d Alias R3G1
CD1d Cellular Expression T; B; Dendritic; Epithelial
CD1d Ligand/Receptor/Association CD1-restricted TCR
CD1d Function Antigen presenting protein
CD1d Summary This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]

Information from NCBI or Wiki

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