CD1b antigens

CD1b antigens general information

CD1b Gene ID 910
CD1b Official Full Name CD1b molecule
CD1b Alias T6
CD1b Cellular Expression T; B; Dendritic; Macrophage
CD1b Ligand/Receptor/Association CD1-restricted TCR
CD1b Function Antigen presenting protein
CD1b Summary This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq, Jul 2008]

Information from NCBI or Wiki

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