CD166 antigens

CD166 antigens general information

CD166 Gene ID 214
CD166 Official Full Name activated leukocyte cell adhesion molecule
CD166 Alias ALCAM
CD166 Cellular Expression T; B; Endothelial; Epithelial; Macrophage; monocytes
CD166 Ligand/Receptor/Association CD6, CD166
CD166 Function Mediates cell adhesion by binding to CD6 for intrathymic T-cell development
CD166 Summary This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2011]

Information from NCBI or Wiki

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