CD161 antigens

CD161 antigens general information

CD161 Gene ID 3820
CD161 Official Full Name killer cell lectin like receptor B1
CD161 Alias NKR-P1A, KLRB1
CD161 Cellular Expression T; NK
CD161 Ligand/Receptor/Association LLT1
CD161 Function Inhibits NK cell mediated cytotoxicity. Induces immature thymocyte proliferation
CD161 Summary Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. [provided by RefSeq, Jul 2008]

Information from NCBI or Wiki

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