| CD157 Gene ID | 683 |
| CD157 Official Full Name | bone marrow stromal cell antigen 1 |
| CD157 Alias | BST-1 |
| CD157 Cellular Expression | T; B; Dendritic; Endothelial; Granulocyte; Macrophage; monocytes; Stem cell |
| CD157 Ligand/Receptor/Association | |
| CD157 Function | Synthesis of cyclic ADP-ribose and putative involvement in pre-B-cell growth |
| CD157 Summary | Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008] |
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