CD157 antigens

CD157 antigens general information

CD157 Gene ID 683
CD157 Official Full Name bone marrow stromal cell antigen 1
CD157 Alias BST-1
CD157 Cellular Expression T; B; Dendritic; Endothelial; Granulocyte; Macrophage; monocytes; Stem cell
CD157 Ligand/Receptor/Association  
CD157 Function Synthesis of cyclic ADP-ribose and putative involvement in pre-B-cell growth
CD157 Summary Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008]

Information from NCBI or Wiki

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