CD154 Gene ID | 959 |
CD154 Official Full Name | CD40 ligand |
CD154 Alias | CD40L, CD40 Ligand, gp39, TRAP |
CD154 Cellular Expression | T; monocytes |
CD154 Ligand/Receptor/Association | CD40 |
CD154 Function | Mediates B-cell proliferation, IgE production and is involved in immunoglobulin class switching |
CD154 Summary | The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008] |
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