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CD138 antigens

CD138 antigens general information

CD138 Gene ID 6382
CD138 Official Full Name syndecan 1
CD138 Alias Syndecan-1, SDC
CD138 Cellular Expression B; Endothelial; Epithelial; Stem cell
CD138 Ligand/Receptor/Association extracellular matrix, FGF
CD138 Function Cell proliferation, cell migration, and cell-matrix interactions
CD138 Summary The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008]

Information from NCBI or Wiki

Tips: We list all the CD antigens according to the specific name of CD molecules.