CD antigens are cells surface proteins as receptors. The CD antigens interaction are fundamental to cell signaling. Signal transduction is the process by which a cell recognizes changes in its environment and transforms that signal into modifications in cellular activity and gene expression. Cells receive information through a class of proteins known as receptors. When such CD antigen activate its receptor, the signal is carried into the cell usually by means of a second messenger.
Sino biological offers a comprehensive set of tools for CD antigens related to cell adhesion research, including recombinant proteins, antibodies (mouse mAbs, rabbit mAbs, and rabbit pAbs), ELISA kits, and ORF cDNA clones.
| Name | Name in pathway | Alias | Function |
|---|---|---|---|
| CD11a | Integrin | LFA-1, LFA1A, ITGAL | Intracellular adhesion and costimulation. |
| CD11c | Integrin | p150, 95, CR4, integrin αX, LFA-1A, ITGAX | Cell adhesion |
| CD18 | Integrin | Integrin β2, ITGB2, MFI7 | Adhesion, cell signaling |
| CD25 | Growth Factor | Tac, p55, IL2RA | Receptor for IL2 |
| CD29 | Integrin | Integrin β1, ITGB1, FNRB | Lymphocyte and endothelial adhesion, lymphocyte trafficking and transvascular migration |
| CD41 | Integrin | ITGA2B | Platelet activation and aggregation. |
| CD49b | Integrin | VLA-2, ITGA2 | Adhesion and platelet aggregation. |
| CD49c | Integrin | VLA-3, ITGA3 | Adhesion and signal transduction |
| CD49e | Integrin | VLA-5, ITGA5 | Adhesion, regulation of cell survival and apoptosis |
| CD49f | Integrin | VLA-6, ITGA6 | Embryogenesis, adhesion and cell migration |
| CD51 | Integrin | Vitronectin receptor, ITGAV, MSK8 | Adhesion and signal transduction |
| CD61 | Integrin | GPIIIa, ITGB3, GP3A | Cell adhesion |
| CD103 | Integrin | HUMINAE, ITGA1 | Lymphocyte retention. Receptor for E-cadherin. |
| CD114 | Cytokine | GCSFR, CSF3R | Myeloid cell proliferation and differentiation |
| CD115 | Cytokine | M-CSFR, c-fms, CSF1R | Monocytic cell proliferation and differentiation |
| CD122 | Growth Factor | IL-2Rβ, IL-2RB | Receptor for IL2 and IL15 |
| CD123 | Growth Factor | IL-3R, IL3RA | Receptor for IL3 |
| CD124 | Growth Factor | IL4RA, IL4R | Receptor for IL4 and IL13 |
| CD125 | Growth Factor | IL5RA, IL5R | Receptor for IL5 |
| CD126 | Growth Factor | IL-6R, IL6R, gp80 | Receptor for IL6 |
| CD127 | Growth Factor | IL-7R, IL7R | Receptor for IL7 |
| CD130 | Growth Factor | IL-6Rβ, gp130, IL6ST | Transmits activities of IL6, IL11, LIF and CNF |
| CD191 | Cytokine | CCR1, MIP-1αR, RANTES-R | Chemotaxis, adhesion |
| CD192 | Cytokine | CCR2, MCP-1-R | Leukocyte chemotaxis and is an HIV co-receptor |
| CD212 | Growth Factor | IL-12-R β1, IL12RB1 | Forms part of the receptor complexes for IL12 and IL23 |
| CD213a1 | Growth Factor | IL-13-R α1, IL13RA1 | Forms part of the receptor complexes for IL13 and IL4 |
| CD215 | Growth Factor | IL15RA | Receptor for IL15. |
| CD221 | Growth Factor | IGF-1 R, IGF1R | Receptor for IGF-I and IGF-II. Mediates mitogenic and anti-apoptotic signals |
| CD344 | GPCR | Frizzled-4, Fz-4, FzD4 | Receptor for Wnt proteins |
| CD350 | GPCR | Frizzled-10, Fz-10, FZD10 | Receptor for Wnt proteins |
| CD360 | Growth Factor | IL-21R | Receptor for interleukin-21. |
