CD antigens / Cluster of Differentiation,are cell surface antigens of leukocytes, and important for immune reactions of organisms. CD antigens found in various immune cell populations like B cells, T cells, Dendritic cells and NK cells. As lymphocytes mature, they express different protein receptors on the cell surface, which can aid in determining the type and maturation stage of the cells being examined. These proteins or antigen markers are called Clusters of Differentiation.
CD antigens serve as receptors and ligands, and regulate cell signalling and adaptive immunity. CD antigens are commonly used for immunology, cancer and stem cell biology research, such as immunotherapy, tumor-associated and drug target.
Key Antigens-Human | Key Antigens-Mouse | |
![]() T Cell |
CD3 CD4 CD8 |
CD3 CD4 CD8 |
![]() B Cell |
CD19 CD20 |
CD19 CD20 |
![]() Dendritic Cell |
CD11c CD123 |
CD11c CD123 |
![]() NK Cell |
CD56 | CD335 |
![]() Stem Cell |
CD34 | CD34 |
![]() Macrophage |
CD14 | CD11b |
Key Antigens-Human | Key Antigens-Mouse | |
![]() Monocyte |
CD33 | CD33 |
![]() Granulocyte |
CD66b | CD66b |
![]() Platelet |
CD41 CD61 CD62 |
CD41 CD9 CD62 |
![]() Erythrocyte |
CD235a | CD235a |
![]() Endothelial |
CD146 | CD31 CD106 CD146 |
![]() Epithelial |
CD326 | CD326 |