Receptors Definition

Receptors are proteins, usually cell surface receptors, which bind to ligands and cause responses in the immune system, including cytokine receptors, growth factor receptor and Fc receptor. Receptors can be found in various immune cells like B cells, T cells, NK cells, Monocytes and stem cells. A molecule that binds to a receptor is called a ligand, and can be a peptide (short-protein) or another small molecule such as a neurotransmitter, hormone, pharmaceutical-drug, toxin, or parts of the outside of a virus or microbe. When a ligand binds to its corresponding receptor, it activates or inhibits the receptor's associated-biochemical pathway.

Receptors can induce cell growth, division and death; control membrane channels or regulate cell binding. Receptors play an important role in signal transduction, immunetherapy and immune responses.

Hot Receptors Molecules Chart

ACVR2A ACVR2B/Activin RIIB MCSF Receptor/CSF1R/CD115
HER2/ERBB2 ERBB3/HER3 EPHA3/Eph Receptor A3
EGFR/HER1 IL3RA/CD123 IL6R/IL-6R/CD126
IL1RL1/IL-1 R4 IGF1R/CD221/IGF-I R LILRB4/CD85k/ILT3
IL17RA/IL-17RA/CD217 Insulin Receptor/INSR/CD220 IL2RA/IL-2RA/CD25
IL-4R/CD124 LILRB2/ILT4/LIR-2 CD122 / IL-2RB
IL7R/IL-7R/CD127 VEGFR2/KDR/Flk-1/CD309 LDLR/LDL R/LDL Receptor
PDGFRB/CD140b TNFR1/TNFRSF1A/CD120a TNFR2/TNFRSF1B/CD120b
4-1BB/TNFRSF9/CD137 TRAIL R1/CD261/TNFRSF10A TRAIL R2/CD262/TNFRSF10B
TRAIL R4/CD264/TNFRSF10D TRAILR3/TNFRSF10C TNFRSF11A
TACI/TNFRSF13B(CD267) HVEM/TNFRSF14/CD270 BCMA/TNFRSF17/CD269
Receptors
Receptors Classification
What are Receptors+
- Receptors Definition
- Cell Surface Receptors
Cytokine Receptors
Growth Factor Receptors
Fc Receptor / FcR
Receptors by Differentiation Cells
Receptors by Functions
Receptors Reagent Products
Receptors by Species