Human DcR3 qPCR Primer Pair
Cat: HP100279
Price:
Size:
Number:
Human DcR3 qPCR Primer Pair: 一般情報
遺伝子情報
種:
Human
製品情報
オリゴヌクレオチドの種類:
qPCR Primers
成分:
1 vial of lyophilized qPCR primer mix (1 nmol each primer, sufficient for 200 numbers of 25 μl reactions).
QPCRプライマーの説明:
Verified forward and reverse primers for analyzing the quantitative expression of gene.
アプリケーション & 品質管理
アプリケーション:
SYBR® Green-based quantitative real-time PCR (qPCR).
品質管理:
The primer mix has been verified to generate satisfactory qPCR data on Roche Applied-science LightCycler® 480 Ⅱ.
保存 & 配送
配送方法:
Lyophilized qPCR primer mix is shipped at ambiente temperatura
保存条件:
The lyophilized product is stable for one year from date of receipt when stored at -20℃.
The suspended product is stable for six months from date of receipt when stored at -20℃.
***Sino biological qEASY qPCR primer pairs are used for SYBR Green-based real-time RT-PCR, The primers are designed by using SBI's proprietary primer design algorithm. Our primer collection covers the entire human genomes. It can be widely applied in the quantitative analysis of gene expression.***
特徴とメリット
独特なプライマー設計
ゲノムDNAの増幅を効果的に回避するために、このプライマーペアには少なくとも１つのプライマーまたは産物がイントロンを横切るように、特定の遺伝子の異なる変異体の保存領域でプライマーを設計します。
厳格なスクリーニング検証プロセス
プラスミド標準品でqPCRプライマーの感度、増幅効率、および特異性をスクリーニングし、陽性組織または細胞で検証し確認します。
均一なPCR条件、操作が簡単で、時間とコストを節約します
~100%という増幅効率で、RNA定量の正確さを保証
Human DcR3 qPCR Primer Pair: 別名
DCR3 qPCR Primer Pairs, Human; DJ583P15.1.1 qPCR Primer Pairs, Human; M68 qPCR Primer Pairs, Human; M68E qPCR Primer Pairs, Human; TNFRSF6B qPCR Primer Pairs, Human; TR6 qPCR Primer Pairs, Human
DcR3 背景情報
Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) also known as DcR3(Decoy Receptor 3) and M68 is the tumor necrosis factor receptor superfamily. DcR3/TNFRSF6B belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript. DcR3/TNFRSF6B is detected in fetal lung, brain and liver. DcR3/TNFRSF6B is also detected in adult stomach, spinal cord, lymph node, trachea, spleen, colon and lung. This protein is highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells.
完全な名称
tumor necrosis factor receptor superfamily member 6b
Related Pathways
-
Death Receptor Signaling
参考文献
- Migone TS, et al. (2002) TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator. Immunity. 16(3): 479-92.
- Takahama Y, et al. (2002) The prognostic significance of overexpression of the decoy receptor for Fas ligand (DcR3) in patients with gastric carcinomas. Gastric Cancer. 5(2): 61-8.
- Zhang J, et al. (2001) Modulation of T-cell responses to alloantigens by TR6/DcR3. J Clin Invest. 107(11): 1459-68.
DcR3 qPCRプライマーペア, Human, 関連製品
If you couldn't find the specific citation, you can:
