SIGNR1 Matched ELISA Antibody Pair Set,Mouse

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SIGNR1 Matched ELISA Antibody Pair Set,Mouse 製品情報

製品名
SIGNR1 Matched ELISA Antibody Pair Set,Mouse
検出原理
Solid Phase Sandwich ELISA
特異性
Quantitative determination of Mouse SIGNR1
線形範囲
6.25-400 pg/mL
ELISA 抗体ペアセット(すぐに使用できません)の成分
1. Capture Antibody 0.4 mg/mL of rabbit anti-mouse CD209B monoclonal antibody. Dilute to a working concentration of 2 μg/mL in CBS before coating. (Catalog: # 50486-R123)
2. Detection Antibody 0.25 mg/mL rabbit anti-mouse CD209B monoclonal antibody conjugated to horseradish-peroxidase (HRP). Dilute to working concentration of 0.5 μg/mL in detection antibody dilution buffer before use. (Catalog: # 50486-R001)
3. Standard Each vial contains 16 ng of recombinant mouse CD209B. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in sample dilution buffer, and a high standard of 0.4 ng/mL is recommended.
製品概要
This SIGNR1 Matched ELISA Antibody Pair Set,Mouse is a solid phase sandwich ELISA for quantitative determination of Mouse SIGNR1 . It contains Mouse SIGNR1 capture antibody, Mouse SIGNR1 detector antibody (HRP) and a highly purified HEK293-expressed recombinant Mouse SIGNR1 protein. This Pair Set is at affordable price for researchers.
配送方法
This Matched ELISA Antibody Pair Set is shipped at ambient temperature.
保存条件
Capture Antibody: Aliquot and store at -20℃ to -80℃ for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Detection Antibody: Protect it from prolonged exposure to light. Aliquot and store at -20℃ to -80℃ and for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Standard: Store lyophilized standard at -20℃ to -80℃ for up to 6 months from date of receipt. Aliquot and store the reconstituted Standard at -80℃ for up to 1 month. Avoid repeated freeze-thaw cycles.

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SIGNR1 Matched ELISA Antibody Pair Set,Mouse: 別名

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SIGNR1 背景情報

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 32 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD29b, also known as SIGNR1, is a C-type lectin receptor. CD29b is present on most regions of mouse brain and found on microglia and dendritic cells but not on neurons or astrocytes. CD29b is implicated in the recently described SIGNR1 complement activation pathway, which operates against capsular polysaccharides in splenic marginal macrophages. CD29b in rat is homologue to SIGNR1 in mouse, both of which are found to mediate the uptake of dextran or CPS14 within the splenic marginal zone.
完全な名称
CD209b antigen
参考文献
  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
  • Park JY, et al. (2009) The C-type lectin CD209b is expressed on microglia and it mediates the uptake of capsular polysaccharides of Streptococcus pneumonia. Neuroscience Letters. 450 (3): 246-51.
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