IL-15 Matched ELISA Antibody Pair Set,Human

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IL-15 Matched ELISA Antibody Pair Set,Human 製品情報

製品名
IL-15 Matched ELISA Antibody Pair Set,Human
検出原理
Solid Phase Sandwich ELISA
特異性
Quantitative determination of Human IL-15
線形範囲
12.5-800 pg/mL
ELISA 抗体ペアセット(すぐに使用できません)の成分
1. Capture Antibody 1 mg/mL of rabbit anti-Human IL-15 monoclonal antibody (in PBS, pH 7.4). Dilute to a working concentration of 0.5 μg/mL in PBS before coating. (Catalog: # 10360-R112)
2. Detection Antibody 0.2 mg/mL of rabbit anti-Human IL-15 monoclonal antibody conjugated to horseradish-peroxidase (HRP) (in PBS, 50 % HRP-Protector, pH 7.4, store at 4℃). Dilute to working concentration of 0.1 μg/mL in Dilution Buffer before use. (Catalog: # 10360-R111)
3. Standard Each vial contains 32 ng of recombinant Human IL-15. Reconstitute with 1 mL Dilution Buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in Dilution Buffer, and a high standard of 800 pg/mL is recommended.
製品概要
This IL-15 Matched ELISA Antibody Pair Set,Human is a solid phase sandwich ELISA for quantitative determination of Human IL-15 . It contains Human IL-15 capture antibody, Human IL-15 detector antibody (HRP) and a highly purified E. coli-expressed recombinant Human IL-15 protein. This Pair Set is at affordable price for researchers.
配送方法
This Matched ELISA Antibody Pair Set is shipped at ambient temperature.
保存条件
Capture Antibody: Aliquot and store at -20℃ to -80℃ for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Detection Antibody: Store at 4℃ and protect it from prolonged exposure to light for up to 6 months from date of receipt. DO NOT FREEZE!
Standard: Store lyophilized standard at -20℃ to -80℃ for up to 6 months from date of receipt. Aliquot and store the reconstituted Standard at -80℃ for up to 1 month. Avoid repeated freeze-thaw cycles.

IL-15 Matched ELISA Antibody Pair Set,Human の画像

IL-15 Matched ELISA Antibody Pair Set,Human: 別名

IL-15 Matched ELISA Antibody Pair Set, Human; Interleukin 15 Matched ELISA Antibody Pair Set, Human

IL-15 背景情報

The protein encoded by IL15 gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported.
完全な名称
interleukin 15
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参考文献
  • Mongini PKA, Gupta R, Boyle E, et al. TLR-9 and IL-15 synergy promotes the in vitro clonal expansion of chronic lymphocytic leukemia B cells. Journal of immunology (Baltimore, Md : 1950). 2015;195(3):901-923.
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