IL-13 Matched ELISA Antibody Pair Set,Human

The online Datasheet here is only a general version, for batch specific information please refer to the hard copy included in the product shipping package.

IL-13 Matched ELISA Antibody Pair Set,Human 製品情報

製品名
IL-13 Matched ELISA Antibody Pair Set,Human
検出原理
Solid Phase Sandwich ELISA
特異性
Quantitative determination of Human IL-13
線形範囲
4.69-300 pg/mL
ELISA 抗体ペアセット(すぐに使用できません)の成分
1. Capture Antibody 0.3 mg/mL of mouse anti-Human IL13 / IL-13 / ALRH monoclonal antibody (in PBS, pH 7.4). Dilute to a working concentration of 2 μg/mL in PBS before coating. (Catalog: # 10369-MM15)
2. Detection Antibody 0.2 mg/mL of mouse anti-Human IL13 / IL-13 / ALRH monoclonal antibody conjugated to horseradish-peroxidase (HRP) (in PBS, 50 % HRP-Protector, pH 7.4, store at 4℃). Dilute to working concentration of 0.5 μg/mL in detection antibody dilution buffer before use. (Catalog: # 10369-MM02T)
3. Standard Each vial contains 27 ng of recombinant Human IL13 / IL-13 / ALRH. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in sample dilution buffer, and a high standard of 300 pg/mL is recommended.
製品概要
This IL-13 Matched ELISA Antibody Pair Set,Human is a solid phase sandwich ELISA for quantitative determination of Human IL-13 . It contains Human IL-13 capture antibody, Human IL-13 detector antibody (HRP) and a highly purified HEK293-expressed recombinant Human IL-13 protein. This Pair Set is at affordable price for researchers.
配送方法
This Matched ELISA Antibody Pair Set is shipped at ambient temperature.
保存条件
Capture Antibody: Aliquot and store at -20℃ to -80℃ for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.
Detection Antibody: Store at 4℃ and protect it from prolonged exposure to light for up to 6 months from date of receipt. DO NOT FREEZE!
Standard: Store lyophilized standard at -20℃ to -80℃ for up to 6 months from date of receipt. Aliquot and store the reconstituted Standard at -80℃ for up to 1 month. Avoid repeated freeze-thaw cycles.

IL-13 Matched ELISA Antibody Pair Set,Human の画像

IL-13 Matched ELISA Antibody Pair Set,Human: 別名

ALRH Matched ELISA Antibody Pair Set, Human; IL-13 Matched ELISA Antibody Pair Set, Human; P600 Matched ELISA Antibody Pair Set, Human

IL-13 背景情報

Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family. IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL-13 Rα1 and IL-13 Rα2). As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses, and diseases. Also, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. IL-13 protein and antibody are more importantly implicated as a central mediator of immunoregulatory processes in various cell types.
完全な名称
interleukin 13
研究分野
参考文献
  • Junttila IS, et al. (2008) Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity. J Exp Med. 205(11): 2595-608.
  • Shimamura T,et al. (2008) Novel role of IL-13 in fibrosis induced by nonalcoholic steatohepatitis and its amelioration by IL-13R-directed cytotoxin in a rat model. J Immunol. 181(7): 4656-65.
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