MTOR cDNA Clone: Expression and Clone Vector / Plasmid

MTOR cDNA / Gene Overview

MTOR cDNA / gene is a gene with protein product which located on 1p36.22. The MTOR gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog. 240 organisms have orthologs with human gene MTOR.

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MTOR cDNA / Gene Function

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]

MTOR cDNA / Gene Sequence

LOCUS
HUMFRAPX 7943 bp mRNA linear PRI 31-DEC-1994
DEFINITION
Human FKBP-rapamycin associated protein (FRAP) mRNA, complete cds.
ACCESSION
L34075
VERSION
L34075.1

This sequence information is just for reference only.

MTOR cDNA / Gene Alias

  • dJ576K7.1 (FK506 binding protein 12-rapamycin associated protein 1)
  • FK506 binding protein 12-rapamycin associated protein 2
  • FKBP12-rapamycin complex-associated protein 1
  • FKBP-rapamycin associated protein
  • FLJ44809
  • mammalian target of rapamycin
  • RAFT1
  • rapamycin and FKBP12 target 1
  • rapamycin associated protein FRAP2
  • rapamycin target protein
  • RAPT1

MTOR cDNA / Gene Expression

Broad expression in testis (RPKM 23.6), brain (RPKM 8.1) and 25 other tissues